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biomcp

bygenomoncology· 1 MCP server

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2.8k

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557

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Category

Research

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TL;DR

One binary. One grammar. Evidence from the biomedical sources you already trust.

How to install biomcp?

genomoncology/biomcp
$git clone https://github.com/genomoncology/biomcp

Installs into the current project.

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Install & use

Install biomcp by running `git clone https://github.com/genomoncology/biomcp`, then use it for the current task and follow its documentation at https://github.com/genomoncology/biomcp.

Files · 1

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README.md
1# BioMCP
2 
3One binary. One grammar. Evidence from the biomedical sources you already trust.
4 
5## What is BioMCP?
6 
7BioMCP is one CLI binary over a single command grammar that reaches ~30 trusted
8biomedical sources (PubMed, ClinVar, ClinicalTrials.gov, OncoKB, Reactome, and
9more). It is also an MCP (Model Context Protocol) server, so the same tools are
10available to AI agents such as Claude Code, Codex, and Claude Desktop.
11 
12BioMCP cuts through the usual biomedical data maze: one query reaches the
13sources that normally live behind different APIs, identifiers, and search
14habits. Researchers, clinicians, and agents use the same command grammar to
15search, focus, and pivot without rebuilding the workflow for each source. You
16get compact, evidence-oriented results across live public data plus local study analytics.
17 
18## Features
19 
20- **Search the literature:** `search article` fans out across PubTator3 and
21 Europe PMC, deduplicates PMID/PMCID/DOI identifiers, and can add a Semantic
22 Scholar leg when your filters support it.
23- **Pivot without rework:** move from a gene, variant, drug, disease, pathway,
24 protein, or article straight into the next built-in view instead of
25 rebuilding filters by hand.
26- **Choose a playbook:** `biomcp skill list` shows shipped worked examples
27 so you can open the matching `biomcp skill <slug>` workflow.
28- **Analyze studies locally:** `study` commands cover local query, cohort, survival,
29 compare, and co-occurrence workflows with native terminal, SVG, and PNG
30 charts for downloaded cBioPortal-style datasets.
31- **Follow the paper trail:** `article citations`, `article references`,
32 `article recommendations`, and `article entities` turn one known paper into a
33 broader evidence map.
34- **Enrich and batch:** use `biomcp enrich` for top-level g:Profiler
35 enrichment and `biomcp batch` for up to 10 focused `get` calls in one
36 command.
37 
38## Quick start
39 
40First useful query in under 30 seconds:
41 
42```bash
43uv tool install biomcp-cli
44biomcp health --apis-only
45biomcp skill list
46biomcp list gene
47biomcp search all --gene BRAF --disease melanoma # unified cross-entity discovery
48biomcp get gene BRAF pathways hpa
49```
50 
51## Installation
52 
53### Binary install
54 
55```bash
56curl -fsSL https://biomcp.org/install.sh | bash
57```
58 
59### PyPI tool install
60 
61```bash
62uv tool install biomcp-cli
63# or: pip install biomcp-cli
64```
65 
66> **PyPI package warning:** install `biomcp-cli`, not `biomcp`. The `biomcp`
67> PyPI package is unrelated to this project.
68 
69MCP Registry ownership marker: `mcp-name: io.github.genomoncology/biomcp`.
70 
71This installs the `biomcp` binary on your PATH.
72 
73### Homebrew
74 
75```bash
76brew tap genomoncology/biomcp
77brew install biomcp
78```
79 
80The separate `genomoncology/homebrew-biomcp` tap repository must exist before these commands can work.
81 
82### Docker
83 
84```bash
85docker run --rm ghcr.io/genomoncology/biomcp --version
86docker run --rm ghcr.io/genomoncology/biomcp list
87docker run --rm -i ghcr.io/genomoncology/biomcp serve
88```
89 
90Use the GHCR image for quick CLI checks or stdio MCP clients without a local install.
91 
92### Claude Code plugin
93 
94Install the `biomcp` binary first, then add the hosted plugin marketplace and
95install the BioMCP plugin in Claude Code:
96 
97```text
98/plugin marketplace add genomoncology/biomcp
99/plugin install biomcp@biomcp
100```
101 
102The plugin wires Claude Code to the local stdio MCP server with `biomcp serve`.
103For guided BioMCP workflows, also install the skill assets below.
104 
105### Codex MCP server
106 
107Install the `biomcp` binary first, then register the same stdio MCP server with
108Codex:
109 
110```bash
111codex mcp add biomcp -- biomcp serve
112```
113 
114### Claude Desktop extension (.mcpb)
115 
116Install BioMCP from the Anthropic Directory in Claude Desktop when that path is
117available for your environment. For local/manual setups, use the JSON MCP
118config below.
119 
120### Install skills
121 
122Install guided investigation workflows into your agent directory:
123 
124```bash
125biomcp skill install ~/.claude --force
126```
127 
128### MCP clients
129 
130```json
131{
132 "mcpServers": {
133 "biomcp": {

Preview

genomoncology/biomcpgenomoncology/biomcp

# BioMCP

One binary. One grammar. Evidence from the biomedical sources you already trust.

## What is BioMCP?

BioMCP is one CLI binary over a single command grammar that reaches ~30 trusted

Repogenomoncology/biomcp
TypeMCP Servers
CategoryResearch
UpdatedJul 2026
LicenseMIT
First seenJul 27, 2026

Tags

MCPaibioinformatics

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