ESM protein language models for embeddings, sequence scoring, structure prediction, and binder design. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) or mutation-effect scores, (2) Getting protein embeddings for clustering or filtering, (3) Predicting complex structures with ESMFold2, (4) Designing binders by inverting ESMFold2, (5) Filtering designs by sequence plausibility.
$npx -y skills add adaptyvbio/protein-design-skills --skill esmInstalls into the current project.
Run `npx skills use "https://github.com/adaptyvbio/protein-design-skills" --skill "adaptyvbio/protein-design-skills/esm"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/adaptyvbio/protein-design-skills" that are relevant to the current task. Run `npx skills add "https://github.com/adaptyvbio/protein-design-skills"` and select the relevant skills, then follow their instructions.