Epialleles are specific DNA methylation patterns that are mitotically and/or meiotically inherited. This package calls and reports cytosine methylation as well as frequencies of hypermethylated epialleles at the level of genomic regions or individual cytosines in next-generation sequencing data using binary alignment map (BAM) files as an input. Among other things, this package can also extract and visualise methylation patterns and assess allele specificity of methylation.
How to install epialleler?
biomate-ai/biomate-bioconductor-kb/epialleler
$npx -y skills add biomate-ai/biomate-bioconductor-kb --skill epiallelerInstalls into the current project.
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Run `npx skills use "https://github.com/biomate-ai/biomate-bioconductor-kb" --skill "biomate-ai/biomate-bioconductor-kb/epialleler"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/biomate-ai/biomate-bioconductor-kb" that are relevant to the current task. Run `npx skills add "https://github.com/biomate-ai/biomate-bioconductor-kb"` and select the relevant skills, then follow their instructions.
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