Systematic 3D interaction calls and differential analysis for Hi-C and HiChIP. The HiC-DC+ (Hi-C/HiChIP direct caller plus) package enables principled statistical analysis of Hi-C and HiChIP data sets – including calling significant interactions within a single experiment and performing differential analysis between conditions given replicate experiments – to facilitate global integrative studies. HiC-DC+ estimates significant interactions in a Hi-C or HiChIP experiment directly from the raw con
$npx -y skills add biomate-ai/biomate-bioconductor-kb --skill hicdcplusInstalls into the current project.
Run `npx skills use "https://github.com/biomate-ai/biomate-bioconductor-kb" --skill "biomate-ai/biomate-bioconductor-kb/hicdcplus"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/biomate-ai/biomate-bioconductor-kb" that are relevant to the current task. Run `npx skills add "https://github.com/biomate-ai/biomate-bioconductor-kb"` and select the relevant skills, then follow their instructions.