MHC (major histocompatibility complex) molecules are cell surface complexes that present antigens to T cells. The repertoire of antigens presented in a given genetic background largely depends on the sequence of the encoded MHC molecules, and thus, in humans, on the highly variable HLA (human leukocyte antigen) genes of the hyperpolymorphic HLA locus. More than 28,000 different HLA alleles have been reported, with significant differences in allele frequencies between human populations worldwide
$npx -y skills add biomate-ai/biomate-bioconductor-kb --skill immunotationInstalls into the current project.
Run `npx skills use "https://github.com/biomate-ai/biomate-bioconductor-kb" --skill "biomate-ai/biomate-bioconductor-kb/immunotation"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/biomate-ai/biomate-bioconductor-kb" that are relevant to the current task. Run `npx skills add "https://github.com/biomate-ai/biomate-bioconductor-kb"` and select the relevant skills, then follow their instructions.