MSA2dist calculates pairwise distances between all sequences of a DNAStringSet or a AAStringSet using a custom score matrix and conducts codon based analysis. It uses scoring matrices to be used in these pairwise distance calcualtions which can be adapted to any scoring for DNA or AA characters. E.g. by using literal distances MSA2dist calculates pairwise IUPAC distances.
$npx -y skills add biomate-ai/biomate-bioconductor-kb --skill msa2distInstalls into the current project.
Run `npx skills use "https://github.com/biomate-ai/biomate-bioconductor-kb" --skill "biomate-ai/biomate-bioconductor-kb/msa2dist"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/biomate-ai/biomate-bioconductor-kb" that are relevant to the current task. Run `npx skills add "https://github.com/biomate-ai/biomate-bioconductor-kb"` and select the relevant skills, then follow their instructions.