byclawbio· 56 skills
Compute pairwise r² between a lead variant and every variant in a window using the 1000 Genomes Phase 3 GRCh38 reference panel, ancestry-stratified. Use when an agent needs LD coloring for a regional plot or LD pruning around a candidate causal variant. Single client (on-demand region fetch from EBI 1000G FTP); no multi-GB cold-start.
$npx -y skills add clawbio/clawbio --skill ld-1000g-region-computeInstalls into the current project.
Run `npx skills use "https://github.com/clawbio/clawbio" --skill "clawbio/clawbio/ld-1000g-region-compute"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/clawbio/clawbio" that are relevant to the current task. Run `npx skills add "https://github.com/clawbio/clawbio"` and select the relevant skills, then follow their instructions.