byholobiomicslab· 58 skills
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Use when you have raw .idat files or beta-valued matrices from HumanMethylation450 (450k) arrays and need to remove low-quality probes, correct for technical artifacts (batch effects, type-2 probe bias), and normalize the data before performing differential methylation analysis or DMR detection.
$npx -y skills add holobiomicslab/asb-skill-collections --skill 450k-array-data-processingInstalls into the current project.
Run `npx skills use "https://github.com/holobiomicslab/asb-skill-collections" --skill "holobiomicslab/asb-skill-collections/450k-array-data-processing"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/holobiomicslab/asb-skill-collections" that are relevant to the current task. Run `npx skills add "https://github.com/holobiomicslab/asb-skill-collections"` and select the relevant skills, then follow their instructions.