bin-level-sequencing-depth-calculation
byholobiomicslab· 58 skills
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Use when you have a cooler file (.cool or .mcool) from a Hi-C or micro-C experiment and need to quantify the total number of sequencing reads assigned to each genomic bin to assess coverage uniformity, identify poorly-sequenced regions, or prepare bin-level weights for downstream normalization.
How to install bin-level-sequencing-depth-calculation?
holobiomicslab/asb-skill-collections/bin-level-sequencing-depth-calculation
$npx -y skills add holobiomicslab/asb-skill-collections --skill bin-level-sequencing-depth-calculationInstalls into the current project.
›Prefer a prompt? Paste this to your agent
Run `npx skills use "https://github.com/holobiomicslab/asb-skill-collections" --skill "holobiomicslab/asb-skill-collections/bin-level-sequencing-depth-calculation"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/holobiomicslab/asb-skill-collections" that are relevant to the current task. Run `npx skills add "https://github.com/holobiomicslab/asb-skill-collections"` and select the relevant skills, then follow their instructions.
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