byholobiomicslab· 58 skills
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Use when you have a cooler Hi-C contact matrix, a set of genomic features (e.g., CTCF peaks, enhancers, or TAD boundaries defined in BED format), and want to quantify average contact patterns around those features to detect local organization principles.
$npx -y skills add holobiomicslab/asb-skill-collections --skill contact-frequency-aggregation-by-genomic-featureInstalls into the current project.
Run `npx skills use "https://github.com/holobiomicslab/asb-skill-collections" --skill "holobiomicslab/asb-skill-collections/contact-frequency-aggregation-by-genomic-feature"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/holobiomicslab/asb-skill-collections" that are relevant to the current task. Run `npx skills add "https://github.com/holobiomicslab/asb-skill-collections"` and select the relevant skills, then follow their instructions.