Build comprehensive DNA methylation maps by aggregating WGBS (Whole Genome Bisulfite Sequencing) data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is DNA methylated/unmethylated in my tissue?" by combining per-CpG methylation data into tissue-level methylation profiles. Handles coverage filtering, identifies hypomethylated regions (HMRs) and partially methylated domains (PMDs), and manages cross-lab variation.
How to install methylation-aggregation?
ammawla/encode-toolkit/methylation-aggregation
$npx -y skills add ammawla/encode-toolkit --skill methylation-aggregationInstalls into the current project.
›Prefer a prompt? Paste this to your agent
Run `npx skills use "https://github.com/ammawla/encode-toolkit" --skill "ammawla/encode-toolkit/methylation-aggregation"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/ammawla/encode-toolkit" that are relevant to the current task. Run `npx skills add "https://github.com/ammawla/encode-toolkit"` and select the relevant skills, then follow their instructions.
Related
6 picksType
- researchInvestigate a question against high-trust primary sources and capture the findings as a Markdown file in the repo.Jul 2026
- analyze-projectRigor Analyze / Rigor Audit read-only skill for deep learning research repositories.Jul 2026
- paper-context-resolverRigor Paper Context helper for README-first deep learning repo reproduction.Jul 2026
- repo-intake-and-planRigor Intake helper for README-first deep learning repo reproduction.Jul 2026
- firecrawl-searchWeb search with full page content extraction. Use this skill whenever the user asks to search the web, find articles, research a topic, look something up, find…Jul 2026
- customer-researchWhen the user wants to conduct, analyze, or synthesize customer research.Jul 2026
