byjaechang-hits· 57 skills
De novo and known TF motif enrichment in ChIP-seq/ATAC-seq peaks via HOMER. findMotifsGenome.pl finds over-represented patterns vs background; annotatePeaks.pl assigns context (TSS distance, gene, repeat). Use after MACS3 to identify enriched TFs, annotate peaks with nearest genes, and validate ChIP-seq via the target motif.
$npx -y skills add jaechang-hits/sciagent-skills --skill homer-motif-analysisInstalls into the current project.
Run `npx skills use "https://github.com/jaechang-hits/sciagent-skills" --skill "jaechang-hits/sciagent-skills/homer-motif-analysis"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/jaechang-hits/sciagent-skills" that are relevant to the current task. Run `npx skills add "https://github.com/jaechang-hits/sciagent-skills"` and select the relevant skills, then follow their instructions.