bymims-harvard· 57 skills
Therapeutic antibody engineering and optimization, lead-to-clinical-candidate. Covers sequence humanization (germline alignment, framework retention), affinity maturation, developability (aggregation, stability, PTMs), structure modeling (AlphaFold/PDB CDR analysis), immunogenicity prediction, and manufacturing feasibility. Use for biologic-drug optimization, mAb design review, biosimilar engineering, and clinical-precedent comparison.
$npx -y skills add mims-harvard/tooluniverse --skill tooluniverse-antibody-engineeringInstalls into the current project.
Run `npx skills use "https://github.com/mims-harvard/tooluniverse" --skill "mims-harvard/tooluniverse/tooluniverse-antibody-engineering"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/mims-harvard/tooluniverse" that are relevant to the current task. Run `npx skills add "https://github.com/mims-harvard/tooluniverse"` and select the relevant skills, then follow their instructions.