tooluniverse-crispr-screen-analysis
bymims-harvard· 57 skills
Analyze CRISPR-Cas9 genetic screens — MAGeCK gene-level scores, sgRNA count QC, replicate correlation, hit prioritization, and pathway GSEA on screen output. Use for genome-wide essentiality screens, synthetic-lethality discovery, dropout vs positive-selection screen analysis, target identification, and resistance-screen interpretation. Includes screen-QC and statistical thresholds.
How to install tooluniverse-crispr-screen-analysis?
mims-harvard/tooluniverse/tooluniverse-crispr-screen-analysis
$npx -y skills add mims-harvard/tooluniverse --skill tooluniverse-crispr-screen-analysisInstalls into the current project.
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Run `npx skills use "https://github.com/mims-harvard/tooluniverse" --skill "mims-harvard/tooluniverse/tooluniverse-crispr-screen-analysis"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/mims-harvard/tooluniverse" that are relevant to the current task. Run `npx skills add "https://github.com/mims-harvard/tooluniverse"` and select the relevant skills, then follow their instructions.
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