tooluniverse-functional-genomics-screens
bymims-harvard· 57 skills
Interpret hits from CRISPR-KO/CRISPRi/shRNA screens by integrating DepMap essentiality, gnomAD constraint scores, pathway context (Reactome, STRING), druggability (DGIdb), and clinical evidence (CIViC, COSMIC). Use for screen-hit prioritization, essentiality ranking, and turning a list of screen hits into a prioritized target shortlist.
How to install tooluniverse-functional-genomics-screens?
mims-harvard/tooluniverse/tooluniverse-functional-genomics-screens
$npx -y skills add mims-harvard/tooluniverse --skill tooluniverse-functional-genomics-screensInstalls into the current project.
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Run `npx skills use "https://github.com/mims-harvard/tooluniverse" --skill "mims-harvard/tooluniverse/tooluniverse-functional-genomics-screens"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/mims-harvard/tooluniverse" that are relevant to the current task. Run `npx skills add "https://github.com/mims-harvard/tooluniverse"` and select the relevant skills, then follow their instructions.
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