bymims-harvard· 57 skills
Transform GWAS signals into drug targets and repurposing opportunities. Connects GWAS-significant loci to causal genes via fine-mapping/eQTL, then to druggable proteins via DGIdb/OpenTargets, then to existing drugs via ChEMBL. Use for GWAS-to-target hypothesis generation, druggable-fraction analysis of disease loci, and human-genetics-validated drug-repurposing prioritization.
$npx -y skills add mims-harvard/tooluniverse --skill tooluniverse-gwas-drug-discoveryInstalls into the current project.
Run `npx skills use "https://github.com/mims-harvard/tooluniverse" --skill "mims-harvard/tooluniverse/tooluniverse-gwas-drug-discovery"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/mims-harvard/tooluniverse" that are relevant to the current task. Run `npx skills add "https://github.com/mims-harvard/tooluniverse"` and select the relevant skills, then follow their instructions.