Inverse-fold a protein backbone (PDB structure) into amino-acid sequence with ProteinMPNN (Dauparas et al. 2022, github.com/dauparas/ProteinMPNN). Reach for this skill to run sequence design on RFdiffusion backbones, to redesign one chain of a PDB while holding interface residues fixed, or to generate a temperature-swept set of sequences for downstream folding.
How to install proteinmpnn?
xuzhougeng/wisp-science/proteinmpnn
$npx -y skills add xuzhougeng/wisp-science --skill proteinmpnnInstalls into the current project.
›Prefer a prompt? Paste this to your agent
Run `npx skills use "https://github.com/xuzhougeng/wisp-science" --skill "xuzhougeng/wisp-science/proteinmpnn"` and follow the generated skill instructions now. Read its complete output, redirecting it to a temporary file first if necessary. Resolve relative paths from the supporting-files directory it provides.
Use the skills in "https://github.com/xuzhougeng/wisp-science" that are relevant to the current task. Run `npx skills add "https://github.com/xuzhougeng/wisp-science"` and select the relevant skills, then follow their instructions.
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