$npx -y skills add Yuan1z0825/nature-skills --skill nature-statisticsAudit, revise, or draft manuscript statistical reporting for Nature / high-impact journal submissions. Use when the user asks to check statistical analysis sections, p values, confidence intervals, sample size, biological versus technical replicates, randomization, blinding, mult
| 1 | # Nature Statistics Reporting Skill |
| 2 | |
| 3 | Use this skill to make manuscript statistics transparent, reproducible, and appropriately bounded. It is a reporting and review skill, not a substitute for a statistician reanalysing raw data unless the user supplies the data and explicitly asks for computation. |
| 4 | |
| 5 | ## Default stance |
| 6 | |
| 7 | - Prioritize design transparency over decorative statistical language. |
| 8 | - Separate three questions: what was measured, what unit was analysed, and what inference was claimed. |
| 9 | - Treat the independent experimental unit as the default `n`; do not silently treat cells, fields of view, repeated readings, spectra, model runs, or technical replicates as independent biological or experimental samples. |
| 10 | - Prefer effect sizes, uncertainty intervals, sample sizes, and exact test definitions over significance-only phrasing. |
| 11 | - State missing information as `AUTHOR_INPUT_NEEDED` instead of inventing sample sizes, tests, software, corrections, exclusion rules, randomization, or blinding. |
| 12 | - If a journal-specific instruction, study-type guideline, or field standard conflicts with this skill, follow the more specific source and mark the source used. |
| 13 | |
| 14 | ## Accepted inputs |
| 15 | |
| 16 | The skill may receive: |
| 17 | |
| 18 | - a Statistical analysis / Methods subsection |
| 19 | - Results paragraphs containing test statistics or p values |
| 20 | - figure panels, legends, captions, or source-data notes |
| 21 | - reviewer comments about statistics |
| 22 | - author notes in Chinese or English |
| 23 | - tables of reported comparisons |
| 24 | - raw or summary data, only when the user wants a concrete reanalysis or figure-statistics check |
| 25 | |
| 26 | If the input is partial, run a bounded audit and state which parts cannot be assessed. |
| 27 | |
| 28 | ## Workflow |
| 29 | |
| 30 | 1. **Classify the task.** Decide whether the user wants audit, rewrite, draft, reviewer-response support, figure-statistics alignment, or data-backed reanalysis. |
| 31 | 2. **Extract the design.** Identify groups, treatments, time points, endpoints, blocking factors, repeated measures, randomization, blinding, exclusions, and missing-data handling. |
| 32 | 3. **Define `n` and replication.** Separate independent experimental units, biological replicates, technical replicates, repeated measures, cells/fields/subsamples, simulations, and pooled observations. |
| 33 | 4. **Map claims to analyses.** For each result claim, record the comparison/model, test family, assumptions, correction strategy, effect estimate, uncertainty, and exact p-value policy. |
| 34 | 5. **Check common failure modes.** Use `references/common-failure-modes.md` when the text involves nested data, many comparisons, cell-level measurements, interaction claims, correlations, regression, outliers, small samples, or significance-only reasoning. |
| 35 | 6. **Check reporting completeness.** Use `references/statistical-reporting.md` to verify that Methods and Results give enough information for readers and reviewers to understand the analysis. |
| 36 | 7. **Align figure statistics.** Use `references/figure-statistics.md` when figure legends, panel labels, stars, error bars, box plots, violin plots, source data, or supplementary figure notes are involved. |
| 37 | 8. **Draft or revise.** Produce conservative, ready-to-paste text. Keep claims within the supplied design and evidence. Do not upgrade statistical association into mechanism or causality. |
| 38 | 9. **Run final QA.** Use `references/reviewer-checklist.md` before final delivery for severity labels, unresolved author questions, and reviewer-facing risk. |
| 39 | |
| 40 | ## Output format |
| 41 | |
| 42 | Unless the user asks for another format, return: |
| 43 | |
| 44 | ```text |
| 45 | Statistics review scope |
| 46 | - Input reviewed: |
| 47 | - Boundary / missing materials: |
| 48 | - Study design readout: |
| 49 | - Independent unit and replication readout: |
| 50 | |
| 51 | Major statistical issues |
| 52 | - [P0/P1/P2] Issue: |
| 53 | Evidence from supplied text: |
| 54 | Why it matters: |
| 55 | Fix: |
| 56 | |
| 57 | Ready-to-paste revision |
| 58 | [Rewritten Statistical analysis / Results / figure legend text] |
| 59 | |
| 60 | AUTHOR_INPUT_NEEDED |
| 61 | - [short factual questions only] |
| 62 | |
| 63 | Reviewer-risk note |
| 64 | - What a statistical reviewer may still challenge: |
| 65 | ``` |
| 66 | |
| 67 | For a clean drafting request with enough information, skip the long issue list and return: |
| 68 | |
| 69 | ```text |
| 70 | Draft Statistical analysis |
| 71 | [ready-to-paste text] |
| 72 | |
| 73 | Reporting notes |
| 74 | - n definition: |
| 75 | - tests/models: |
| 76 | - multiple comparisons: |
| 77 | - software/version: |
| 78 | - unresolved fields: |
| 79 | ``` |
| 80 | |
| 81 | ## Red lines |
| 82 | |
| 83 | - Do not invent p values, sample sizes, degrees of freedom, confidence intervals, software versions, correction metho |