qsong-github/drugclaw
57 skills
$npx skills add qsong-github/drugclawSkillInstalls
ade_corpus**ADE Corpus V2** — Adverse Drug Event relation extraction dataset from annotated PubMed case reports.adrecsQuery the ADReCS (Adverse Drug Reaction Classification System) v3.3 database. Use whenever the user asks about adverse drug reactions, drug safety profiles, ADR classification, ADR severity/frequency,atcQuery the WHO ATC/DDD Classification System. Use whenever the user asks about ATC codes, drug classification hierarchy, Defined Daily Doses (DDD), or wants to look up drugs by ATC class or find the ATbindingdbQuery the BindingDB drug-target binding affinity database. Use whenever the user asks about protein-ligand binding data, affinity measurements (Ki, IC50, Kd, EC50), or wants to look up binding partnercadecQuery the CADEC (CSIRO Adverse Drug Event Corpus). Use whenever the user asks about adverse drug event mentions in consumer health text, entity annotations from patient forum posts, MedDRA/SNOMED-CT nchebiQuery the ChEBI (Chemical Entities of Biological Interest) database. Use whenever the user asks about small molecule identifiers, chemical ontology roles, molecular formulae, SMILES, InChI, synonyms, chemblQuery the ChEMBL database for drug molecules, bioactivity data, and drug targets via the ChEMBL REST API. Use whenever the user asks about drug properties (molecular weight, logP, Lipinski violations)cpic> Clinical Pharmacogenomics Implementation Consortium — gene-based prescribing guidelines > **Category:** Drug-centric | **Type:** DB | **Subcategory:** Drug Knowledgebase > **API:** `https://api.dailymedQuery DailyMed for FDA drug label / package insert information. Use whenever the user asks about drug labeling, SPL documents, prescribing information, NDC codes, or needs to look up current FDA-approddi_corpus| Field | Value | |-------|-------| | **Resource** | DDI Corpus 2013 | | **Category** | Drug-centric / Drug NLP & Text Mining | | **Source** | [GitHub](https://github.com/isegura/DDICorpus) | | **PapeddinterQuery the DDInter drug-drug interaction database. Use whenever the user asks about drug-drug interactions, DDI severity levels, or wants to look up interactions for a drug name or DDInter ID.dgidbQuery the DGIdb (Drug-Gene Interaction Database) for drug-gene interactions, gene druggability categories, and drug target information. Use whenever the user asks about drug targets, druggable genes, dili`DILISkill` uses live ChEMBL REST endpoints for hepatotoxicity-related evidence.dilirankQuery the DILIrank/FDA Liver Toxicity Knowledge Base (LTKB). Use whenever the user asks about drug-induced liver injury (DILI) risk, hepatotoxicity classification, or wants to look up any drug (by namdrkgQuery the DRKG (Drug Repurposing Knowledge Graph). Use whenever the user asks about drug–gene, drug–disease, gene–disease, or other biomedical entity relationships in a knowledge-graph context, drug rdrugbankQuery a locally downloaded DrugBank database. Use whenever the user asks about drug information, drug targets, drug-drug interactions, drug categories, or wants to look up any entity (DrugBank ID, drudrugcentralQuery the DrugCentral drug pharmacology database. Use whenever the user asks about approved drug structures, drug targets, pharmacological actions, or wants to look up any entity (drug name, DrugCentrdrugcombQuery the DrugComb drug combination database for cancer cell-line synergy and sensitivity data. Use whenever the user asks about drug combinations, synergy scores (ZIP/Bliss/Loewe/HSA), combination sedrugcombdbQuery canonical DrugCombDB combination records. Use when the user asks about drug pairs, synergy values, or cell-line-specific combination evidence.drugmechdbQuery the DrugMechDB drug mechanism-of-action database. Use whenever the user asks about drug mechanisms, drug-to-disease paths, biological targets of a drug, or wants to look up any biomedical entitydrugprotQuery drug/chemical and gene/protein entities in the **BioCreative VII DrugProt** dataset. Returns annotated relations (e.g., INHIBITOR, ACTIVATOR, SUBSTRATE) between chemicals and genes/proteins fromdrugrepobankQuery the DrugRepoBank drug repurposing evidence database. Use whenever the user asks about repurposing candidates, drug–disease–target repurposing evidence, or wants to look up any entity (drug name,drugs_com_reviewsQuery the DrugLib.com Drug Review Dataset (UCI #461). Use whenever the user asks about patient drug reviews, drug effectiveness ratings, side-effect profiles, or condition-specific treatment experiencfaersQuery the FDA Adverse Event Reporting System (FAERS) via openFDA API. Use whenever the user asks about adverse drug reactions, side effects, drug safety signals, or wants to look up reported adverse efda_orange_bookQuery or inspect the FDA Orange Book - FDA-Approved Drug Products Listing resource for drug-centric tasks with emphasis on drug knowledgebase Use whenever Codex needs the calling pattern, downloadablegdkdQuery the Gene-Drug Knowledge Database (GDKD) for variant-specific gene–drug associations in oncology. Use when the user asks about cancer genomic biomarkers, drug sensitivity/resistance by gene or vagdsc| Field | Value | |---|---| | Category | Drug-centric | | Subcategory | Drug Molecular Property | | Source | Sanger / Wellcome Trust | | Datasets | **screened_compounds** (drug list), **GDSC1/GDSC2** iupharQuery the IUPHAR/BPS Guide to Pharmacology REST API for drug targets, ligands (drugs/compounds), and their interactions. Use whenever the user asks about pharmacological targets, receptor–ligand relatkegg_drug> Approved drugs — structures, targets, pathways & drug-drug interactions > **Category:** Drug-centric | **Type:** DB | **Subcategory:** DDI > **API:** `https://rest.kegg.jp` (free, no key requirelivertoxLookup LiverTox drug entries using the canonical packaged fixture file.mecddiQuery the MecDDI mechanism-based drug-drug interaction database. Use whenever the user asks about drug-drug interactions, DDI mechanisms (PK/PD), enzyme or transporter-mediated interactions, or wants medlineplusQuery MedlinePlus for consumer-oriented drug and health-topic information. Accepts drug names, RxCUI codes, NDC codes, or ICD-10-CM diagnosis codes. Uses two free, keyless NLM APIs: the Web Service (kmolecular_targetsQuery the NCI CCDI Molecular Targets Platform (pediatric oncology) for targets (genes), diseases, drugs, and target-disease associations via its public GraphQL API. Auto-detects entity type from inpumolecular_targets_dataQuery the NCI-60 Molecular Target (Protein) database from the Developmental Therapeutics Program. Use when the user asks about protein expression of drug targets across the NCI-60 cancer cell line panndfrtQuery NDF-RT (National Drug File Reference Terminology) via the NCI EVS REST API. Use when looking up drug mechanisms of action, physiological effects, pharmacologic classes, chemical structures, or dnsidesQuery the nSIDES drug side effect databases (OnSIDES, OffSIDES, KidSIDES). Use whenever the user asks about drug adverse reactions, side effects, off-label safety signals, or pediatric drug safety foropen_targetsQuery the Open Targets Platform for drug-target-disease associations. Use whenever the user asks about drug targets, gene-disease associations, drug indications, clinical trial phases, or wants to looopenfdaQuery FDA drug labeling data via openFDA. Use whenever the user asks about drug prescribing information — indications, warnings, dosage, adverse reactions, contraindications, or administration routes.oreganoQuery the OREGANO knowledge graph for computational drug repurposing. Use whenever the user asks about drug–target–disease–gene–pathway relationships, compound cross-references, drug repurposing hypotpharmgkbQuery ClinPGx (PharmGKB) and CPIC for pharmacogenomics data. Use whenever the user asks about gene-drug interactions, pharmacogenomics clinical annotations, drug-metabolizing enzymes, CPIC guidelines,pharmkgQuery the PharmKG knowledge graph (180k entities, 39 relation types, >1M triples). Use whenever the user asks about biomedical relationships among genes, drugs/chemicals, and diseases — e.g. drug–genepheeQuery the PHEE pharmacovigilance event extraction dataset. Use whenever the user asks about annotated adverse drug events, pharmacovigilance case reports, drug–effect associations from medical literatpsytarQuery the PsyTAR psychiatric adverse-reaction corpus. Use when the user asks about patient-reported ADRs, withdrawal symptoms, drug indications, or effectiveness for Zoloft, Lexapro, Cymbalta, or EfferepodbQuery the RepoDB drug repurposing database. Use whenever the user asks about drug-disease associations, drug repurposing candidates, or wants to look up any entity (drug name, indication, DrugBank ID,repurposedrugsQuery the RepurposeDrugs single-agent drug repurposing database. Use whenever the user asks about drug-disease repurposing associations, clinical trial phases for repurposed drugs, or wants to look uprepurposing_hubQuery the Broad Institute Drug Repurposing Hub (~6,800 compounds). Look up drugs by name, gene target, MOA, disease area, Broad ID, or InChIKey. Returns clinical phase, mechanism of action, targets, rxnormQuery the RxNorm drug naming and normalization API. Use whenever the user asks to look up an RxCUI, normalize a drug name, find drug interactions, retrieve brand/trade names, or resolve any clinical dsematyp> Drug-Disease Association Knowledge Graph from literature mining + TTD > **Category:** Drug-centric | **Type:** KG | **Subcategory:** Drug-Disease Associations > **Access:** Local files (downloadsider**Category:** Drug-centric | **Type:** DB | **Subcategory:** Adverse Drug Reaction (ADR) **Link:** http://sideeffects.embl.de/ | **Paper:** https://doi.org/10.1093/nar/gkv1075stitchQuery the STITCH chemical-protein interaction database. Use whenever the user asks about chemical-protein interactions, drug-target binding, compound action modes, or wants to look up any entity (chemtac2017Query TAC 2017 ADR annotated drug labels for adverse drug reactions. Use whenever the user asks about ADRs extracted from FDA drug labels, MedDRA-normalized adverse reactions, or wants to look up a drtarkgQuery canonical TarKG drug-target triplets. Use when the user asks about drug-target interactions, relation labels, disease/pathway context, or quick lookups for drugs/targets in TarKG.ttdQuery the Therapeutic Target Database (TTD) for drug-target-disease interaction data. Use this skill when the user asks about therapeutic targets, drugs, diseases, or their relationships — including tunid3UniD3 is a multi-knowledge-graph built from 150,000+ PubMed articles, stored as 6 GraphML files. It supports drug-disease matching, effectiveness assessment, and drug-target analysis.unitoxQuery the UniTox drug toxicity database. Use whenever the user asks about organ-system toxicity ratings for a drug, multi-organ toxicity profiles, or wants to look up any entity (drug name, SMILES, SPwebmdQuery the WebMD Drug Reviews dataset (~362 k patient reviews, 2007–2020). Use whenever the user asks about patient-reported drug effectiveness, ease of use, satisfaction ratings, side effects, or reviwho_emlQuery the WHO Model List of Essential Medicines (23rd list, 2023). Use whenever the user asks about essential medicines, WHO-recommended drugs, dosage forms, therapeutic sections, or AWaRe antibiotic